PCR – Bacterial Vaginitis/Vaginosis

Clinical Services

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Advanced PCR Testing for Women’s Health: Clear Answers for a Common, Complex Condition

Bacterial Vaginitis/Vaginosis (BV) is the most common vaginal condition in women of reproductive age, yet it is frequently underdiagnosed, recurrent, and misunderstood. Traditional diagnostic methods may not fully capture the polymicrobial nature of BV or identify co-infections that influence symptoms or recurrence.

Our comprehensive PCR panel provides accurate, organism-level detection from a single vaginal swab supporting confident diagnosis and informed clinical decision making.

Why Comprehensive PCR Testing for BV Matters

Common

BV affects approximately 1 in 3 women ages 14-49 in the U.S., making it the most prevalent vaginal condition in this population.

Often Asymptomatic

Up to 50% of women with BV report no symptoms, allowing infection to persist undetected and untreated.

Clinically Significant

BV is associated with increased susceptibility to sexually transmitted infections, including HIV, chlamydia, gonorrhea, and HSV.

Impact Beyond Symptoms

BV has been linked to serious reproductive and pregnancy complications, including:

  • Preterm birth
  • Premature rupture of membranes
  • Postpartum and post-procedural infections

One Sample. Comprehensive Insight. PCR Testing Sets the Standard for Sensitive, Specific Pathogen Detection

Chlamydia

Pathogens in the Panel

Atopobium vaginae (Fannyhessa)

Bacterial Vaginosis Associated Bacteria type 2 (BVAB2)

Chlamydia trachomatis

Candida albicans

Candida dublienesis

Candida glabrata

Candida krusei

Candida parapsilosis

Candida tropicalis

Gardnerella vaginalis

Lactobacillus

Megasphaera type 1

Mycoplasma genitalium

Neisseria gonorrhoeae (Gonorrhea)

Trichomonas vaginalis

Ureaplasma urealyticum

Recurrent BV is Common

30-50% of patients experience recurrence within 3-6 months. Persistent symptoms may be driven by:

  • Polymicrobial infections
  • Coexisting pathogens not identified by traditional testing
  • Biofilm-forming organisms

Limitations of Traditional Diagnostic Methods

Wet mount microscopy and Amsel/Nugent scoring remain widely used but have important limitations:

  • Operator-dependent sensitivity
  • Inability to identify specific causative organisms
  • Limited insight into mixed infections

Our fully automated, PCR workflow reduces manual handling, eliminates operator variability, delivers consistent and reproducible results from sample to report.

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